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A-T pairs

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Molecules That Read Grooving on DNA in a Minor Way

Posted by Jim Clark on 16th April in A-T pairs

For several years now, chemists and biologists have been intrigued with DNA “antisense” technology. For example, chemists have designed modified RNAs which, through complementary base-pairing, can target specific regions of viral RNA. Such molecules are of interest as potential antiviral drugs. Similarly, it is possible to design oligonucleotides that are complementary to a target region [...]

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